Homoharringtonine 98% CAS 26833-87-4
- Umlinganiswa
Le mveliso luhlobo lomgubo olumhlophe okanye olutyheli olusemgangathweni okanye i-amorphous loose solid, kunye nokungeniswa kokufuma, umbala uba mnyama xa kukhanya.
Le mveliso inyibilika ngokulula kwi-methanol, i-ethanol okanye i-trichloromethane, i-soluble kancinane emanzini okanye kwi-ether. - Indawo yokuhlanganisa
Indawo yokunyibilika yale mveliso (ngokubanzi 0612) yi-143~147°C. - Chonga
.Thatha malunga ne-0.5mg yale mveliso, yongeza i-1mL yamanzi ukuyinyibilikisa, kwaye wongeze i-1 drop ye-bismuth potassium iodide isisombululo sokuvavanya ukuvelisa i-orange precipitate ebomvu.
.thatha malunga ne-1mg yale mveliso, yongeza malunga ne-1mg ye-asidi eguqula umbala, yongeza i-5 ukuya kwe-10 ye-sulfuric acid, kwaye uyifudumeze kwindawo yokuhlambela amanzi ka-50 ukuya ku-60 ° C imizuzu embalwa, oko kukuthi, i-purplish ebomvu.
.thatha umxholo wesisombululo semveliso yovavanyo phantsi komlinganiselo, ngokwe-UV-visible spectrophotometry (umgaqo jikelele 0401) ukuzimisela, kwi-288nm wavelength inomlinganiselo ophezulu wokufunxa.
.ipateni yokufunxa ukukhanya kwe-infrared yale mveliso kufuneka ihambelane nepateni yokulawula (i-spectrum set 420 figure). - Ukomisa ilahleko
Thatha le mveliso, i-phosphorus pentoxide njenge-desiccant, yomile phantsi koxinzelelo kwisisindo esiqhubekayo, ukulahlekelwa kwesisindo akuyi kudlula i-2.0% (umgaqo jikelele we-0831). - Ukuzimisela komxholo
Ngokutsho kolwelo oluphezulu lwechromatography (umgaqo jikelele 0512) ukuzimisela.
Isisombululo sovavanyo
Thatha malunga ne-20mg yale mveliso, uyilinganise ngokuchanekileyo, uyibeke kwibhotile ye-100mL, yongeza i-methanol ye-5mL, xubha ukutshabalalisa, udibanise ngamanzi kwisikali, ugubungele kakuhle, ulinganise ngokuchanekileyo i-2mL, uyibeke kwibhotile ye-20mL, yihlambulule. ngamanzi ukuya kwisikali, vuthulula kakuhle.
Isisombululo seReferensi
Thatha malunga ne-20mg yemveliso yereferensi ye-harringtonine, yilinganise ngokuchanekileyo, uyibeke kwibhotile yokulinganisa i-100mL, yongeza i-5mL methanol, xubha ukuchithwa, udibanise ngamanzi kwisikali, ugubungele kakuhle, ulinganise i-2mL ngokuchanekileyo, uyibeke kwi-20mL. ibhotile yokulinganisa, yihlambulule ngamanzi kwisikali, xubha kakuhle.
Indlela yokulinganisa
Isisombululo sovavanyo kunye nesisombululo solawulo silinganiswe ngokuchanekileyo, sifakwe kwi-chromatograph yolwelo ngokulandelelana, kwaye i-chromatogram yarekhodwa.Indawo encopho ibalwa ngendlela yomgangatho wangaphandle. - Udidi
Iziyobisi ze-Antitumor. - Lay by
Gcina ekukhanyeni, tywina kwaye ugcine kwindawo epholileyo. - Ukulungiselela
Isitofu seHarringtonine. - Ulwazi lokhuseleko
- Xa udibana namehlo, hlambulula ngokukhawuleza ngamanzi amaninzi kwaye ufune iingcebiso zonyango.
- Khulula ngoko nangoko zonke iimpahla ezosulelekileyo.
- Nxiba iimpahla ezifanelekileyo zokukhusela, iiglavu kunye nokukhusela amehlo / ubuso.
- Kwimeko yengozi okanye ukuba uziva ungaphilanga, funa ingcebiso kagqirha ngokukhawuleza (bonisa ilebhile apho kunokwenzeka).
- Ityhefu kakhulu ngokuphefumla, xa udibana nesikhumba kwaye ukuba uginyiwe.
