I-Homoharringtonine 98% CAS 26833-87-4
- Umlingiswa
Lo mkhiqizo uwuhlobo lwempushana yekhwalithi emhlophe noma ephuzi noma okuqinile kwe-amorphous okuxekethile, ngokungeniswa komswakama, umbala uba mnyama uma kukhanya.
Lo mkhiqizo uncibilika kalula ku-methanol, ethanol noma ku-trichloromethane, uncibilika kancane emanzini noma ether. - Iphuzu lokuhlanganisa
Indawo encibilikayo yalo mkhiqizo (okujwayelekile 0612) ingu-143~147°C. - Khomba
.Thatha cishe u-0.5mg walo mkhiqizo, engeza u-1mL wamanzi ukuze uwancibilikise, bese wengeza ithonsi elilodwa lesixazululo sokuhlola i-bismuth potassium iodide ukuze ukhiqize imvula ebomvu ewolintshi.
.thatha cishe i-1mg yalo mkhiqizo, engeza cishe i-1mg ye-asidi eshintsha umbala, engeza amaconsi angu-5 kuya kwangu-10 e-sulfuric acid, futhi uyishise emanzini okugeza angu-50 kuya ku-60 ° C imizuzu embalwa, okungukuthi, i-purplish ebomvu.
.thatha okuqukethwe kwesixazululo somkhiqizo wokuhlola ngaphansi kwesilinganiso, ngokuya nge-UV-visible spectrophotometry (umthetho ojwayelekile 0401), ku-288nm wavelength inokumuncwa okuphezulu.
.iphethini yokumunca ukukhanya kwe-infrared yalo mkhiqizo kufanele ihambisane nephethini yokulawula (i-spectrum set 420 figure). - Ukomisa ukulahlekelwa
Thatha lo mkhiqizo, i-phosphorus pentoxide njenge-desiccant, yomile ngaphansi kwengcindezi yesisindo esiqhubekayo, ukulahlekelwa isisindo ngeke kudlule i-2.0% (umthetho jikelele we-0831). - Ukuzimisela kokuqukethwe
Ngokusho kokusebenza okuphezulu kwe-chromatography ye-liquid (umthetho ojwayelekile 0512) ukuzimisela.
Isixazululo sokuhlola
Thatha cishe u-20mg walo mkhiqizo, ukale kahle, uwubeke ebhodleleni elingu-100mL, engeza i-methanol engu-5mL, unyakazise ukuze uhlakaze, uhlambulule ngamanzi esikalini, unyakazise kahle, ulinganise ngokunembile u-2mL, ulibeke ebhodleleni elingu-20mL, lihlambulule. ngamanzi esikalini, qhaqhazela kahle.
Isixazululo sereferensi
Thatha cishe u-20mg womkhiqizo wereferensi we-harringtonine, uyikale ngokunembile, uyibeke ebhodleleni lokulinganisa elingu-100mL, engeza i-methanol engu-5mL, inyakazise ukuze incibilike, ihlanjululwe ngamanzi esikalini, inyakazise kahle, ikala u-2mL ngokunembile, uyibeke ku-20mL. ibhodlela lokulinganisa, lihlambulule ngamanzi esikalini, shake kahle.
Indlela yokulinganisa
Isixazululo sokuhlola nesixazululo sokulawula kukalwe ngokunembile, kwajovwa ku-chromatograph ewuketshezi ngokulandelana, futhi i-chromatogram yarekhodwa.Indawo ephakemeyo ibalwa ngendlela yangaphandle evamile. - Isigaba
Izidakamizwa ze-Antitumor. - Lay by
Gcina ekukhanyeni, vala futhi ugcine endaweni epholile. - Ukulungiselela
Umjovo we-Harringtonine. - Ulwazi lwezokuphepha
- Uma uthintana namehlo, hlambulula ngokushesha ngamanzi amaningi futhi ufune iseluleko sezokwelapha.
- Khumula ngokushesha zonke izingubo ezingcolile.
- Gqoka izingubo ezifanele zokuzivikela, amagilavu kanye nokuvikela amehlo/ubuso.
- Esimeni sengozi noma uma uzizwa ungaphilile, funa iseluleko sezokwelapha ngokushesha (bonisa ilebula lapho kungenzeka khona).
- Kunobuthi kakhulu ngokuhogela, lapho uthintana nesikhumba futhi uma ugwinyiwe.
