Pregabalin, inowanzo zivikanwa nezita rayo rekuti Lyrica, mushonga unoshandiswa kurapa mamiriro akasiyana siyana sekurwadziwa kweuropathic, fibromyalgia, pfari, uye generalized kusagadzikana kusagadzikana.Iyo ndeyekirasi yemishonga inonzi anticonvulsants, iyo inoshanda nekuderedza kusagadzikana kwemagetsi muuropi.Asi wakambozvibvunza here kuti pregabalin inoshanda sei mumuviri?
Chiito chePregabalin chinonyanya kuenderana nekukwanisa kwayo kusunga kune imwe mhando yekarusiyamu chiteshi mukati mepakati tsinga system.Aya machani anobatanidzwa mukuburitswa kwemaneurotransmitters, ari makemikari nhume dzinotumira masaini pakati pemasero etsinga.Nekusunga kumatanho aya, pregabalin inoderedza kuburitswa kwemamwe maneurotransmitters, anosanganisira glutamate, norepinephrine, uye substance P. Iyi modulation yeneurotransmitter release inotendwa kuti inobatsira kune pregabalin’s therapeutic effects.
Imwe yenzira dzakakosha dzekuita kwe pregabalin kugona kwayo kuderedza kuburitswa kwe glutamate, iyo yekutanga excitatory neurotransmitter mukati mepakati tsinga system.Nokuita kudaro, pregabalin inobatsira kuderedza kusaina kwakanyanyisa pakati pemasero etsinga, ayo anowanzo kubatanidzwa nemamiriro ezvinhu akadai sekurwadziwa kweuropathic uye pfari.Mhedzisiro iyi inofungidzirwa kuti inobatsira mukukwanisa kwepregabalin kubvisa marwadzo uye kuderedza kuita kwekubata.
Pamusoro pemigumisiro yaro pa glutamate, pregabalin inoderedzawo kusunungurwa kwe norepinephrine, neurotransmitter inobatanidzwa mukupindura kwekunetseka kwemuviri uye kugadzirisa kurwadziwa.Nokugadzirisa kusunungurwa kwe norepinephrine, pregabalin inogona kubatsira kuderedza zviratidzo zvehutano hwepfungwa huzhinji uye fibromyalgia, iyo yose inofungidzirwa kuti inosanganisira dysregulation yehutano hwekupindura kwemuviri.
Uyezve, pregabalin yakaratidzwa kuderedza kusunungurwa kwezvinhu P, neurotransmitter inobatanidzwa mukuparadzira zviratidzo zvinorwadza mumuzongoza.Nokuderedza kusunungurwa kwezvinhu P, pregabalin inogona kubatsira kuderedza marwadzo europathic, ayo anowanzoonekwa nekurwadziwa kusingawanzoitiki muhutano hwemagetsi.
Pakazere, chiito che pregabalin chakaoma uye chinosanganisira modulation ye neurotransmitter kuburitswa mukati mepakati tsinga system.Nekunongedza nzira dzekarusiyamu dzakananga uye nekuderedza kuburitswa kwemaurotransmitters akakosha, pregabalin inogona kupa kurapa kwemhando dzakasiyana dzemamiriro, kusanganisira neuropathic kurwadziwa, pfari, fibromyalgia, uye generalized kusagadzikana kusagadzikana.
Zvakakosha kuziva kuti nepo pregabalin nzira yekuita ichinyatsonzwisiswa, mhinduro dzega dzega kumushonga dzinogona kusiyana.Vamwe vanhu vanogona kuwana zororo rakakura kubva kuzviratidzo zvavo, nepo vamwe vangasapindurawo.Uyezve, semishonga yose, pregabalin inogona kuva nemigumisiro, uye zvakakosha kukurukura chero zvinonetsa nemupi wako wehutano.
Mukupedzisa, kunzwisisa chiito che pregabalin kunogona kupa ruzivo rwakakosha kuti mushonga uyu unoshanda sei kuderedza hutano hwakasiyana.Nekunangana neakananga neurotransmitter masisitimu mukati mepakati tsinga system, pregabalin inopa yakasarudzika nzira yekuzorodza zviratidzo.Kana iwe uine chero mibvunzo kana kunetsekana nezve pregabalin, iva nechokwadi chekutsvaga nhungamiro kubva kune nyanzvi yezvehutano.
Nguva yekutumira: Feb-17-2024
