Pregabalin, izwi cyane ku izina ryayo yitwa Lyrica, ni imiti ikoreshwa mu kuvura indwara zitandukanye nk'ububabare bwa neuropathique, fibromyalgia, epilepsy, n'indwara yo guhangayika muri rusange.Ni mubyiciro byibiyobyabwenge byitwa anticonvulsants, bikora mukugabanya ibikorwa byamashanyarazi bidasanzwe mubwonko.Ariko wigeze wibaza uburyo pregabalin ikora mumubiri?
Igikorwa cya Pregabalin gifitanye isano cyane cyane nubushobozi bwacyo bwo guhuza ubwoko bwihariye bwumuyoboro wa calcium muri sisitemu yo hagati.Iyi miyoboro igira uruhare mukurekura neurotransmitter, aribwo butumwa bwa chimique butanga ibimenyetso hagati ya selile.Muguhuza iyi miyoboro, pregabalin igabanya irekurwa rya neurotransmitter zimwe na zimwe, harimo glutamate, norepinephrine, nibintu P. Iyi modulisiyo yo kurekura neurotransmitter yizera ko igira uruhare mu kuvura pregabalin.
Bumwe mu buryo bwingenzi bwibikorwa bya pregabalin nubushobozi bwayo bwo kugabanya irekurwa rya glutamate, primaire yibanze ya neurotransmitter muri sisitemu yo hagati.Kubikora, pregabalin ifasha kugabanya ibimenyetso birenze urugero hagati ya selile nervice, bikunze kuba bifitanye isano nuburwayi nkububabare bwa neuropathique na epilepsy.Izi ngaruka zitekerezwa kugira uruhare mubushobozi bwa pregabalin bwo kugabanya ububabare no kugabanya ibikorwa byo gufatwa.
Usibye ingaruka zabyo kuri glutamate, pregabalin inagabanya irekurwa rya norepinephrine, neurotransmitter igira uruhare mu gukemura ibibazo by'umubiri no gutunganya ububabare.Muguhindura irekurwa rya norepinephrine, pregabalin irashobora gufasha kugabanya ibimenyetso byindwara rusange yo guhangayika hamwe na fibromyalgia, byombi bikekwa ko bikubiyemo kutagabanya uburyo bwo gukemura ibibazo byumubiri.
Byongeye kandi, pregabalin yerekanwe kugabanya irekurwa ryibintu P, neurotransmitter igira uruhare mu kwanduza ibimenyetso byububabare mu ruti rwumugongo.Mugabanye kurekura ibintu P, pregabalin irashobora gufasha kugabanya ububabare bwa neuropathique, bukunze kurangwa no gutunganya ububabare budasanzwe muri sisitemu yimitsi.
Muri rusange, ibikorwa bya pregabalin biragoye kandi bikubiyemo guhindura irekurwa rya neurotransmitter muri sisitemu yo hagati.Muguhitamo imiyoboro yihariye ya calcium no kugabanya irekurwa ryingenzi rya neurotransmitter, pregabalin irashobora gutanga inyungu zo kuvura kubintu bitandukanye, harimo ububabare bwa neuropathique, epilepsy, fibromyalgia, hamwe nindwara rusange yo guhangayika.
Ni ngombwa kumenya ko mugihe uburyo bwa pregabalin bwibikorwa bwumvikana neza, ibisubizo byabantu kumiti birashobora gutandukana.Abantu bamwe barashobora kuruhuka cyane kubimenyetso byabo, mugihe abandi nabo ntibabyitabira.Byongeye kandi, kimwe n'imiti yose, pregabalin irashobora kugira ingaruka, kandi ni ngombwa kuganira kubibazo byose hamwe nushinzwe ubuzima.
Mu gusoza, gusobanukirwa nigikorwa cya pregabalin birashobora gutanga ubushishozi bwukuntu iyi miti ikora kugirango igabanye ubuzima butandukanye.Mugukoresha sisitemu yihariye ya neurotransmitter muri sisitemu yo hagati yo hagati, pregabalin itanga uburyo butandukanye bwo kugabanya ibimenyetso.Niba ufite ikibazo cyangwa impungenge zijyanye na pregabalin, menya neza ko ushaka ubuyobozi kubashinzwe ubuzima.
Igihe cyo kohereza: Gashyantare-17-2024
